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100 Years of Insulin: A Century of Innovation for Diabetics

100 Years of Insulin: A Century of Innovation for Diabetics

  

Diabetes has plagued mankind for thousands of years. While the real causes of diabetes and insulin have been discovered in the last hundred years, inventions to treat diabetes have not stopped with insulin alone in the last century; New ideas about this disease are coming out. New drugs have been developed that not only keep blood sugar levels in check but also deal with heart-related complications that have reduced the mortality rate of diabetics.

When it comes to diabetes, the first thing that comes to mind most people nowadays is oral therapy. But did you know that this beneficial insulin is the first successful medicine to prolong the life of diabetic patients? Insulin deserves credit for improving the luxury of their time in the sophisticated advancement of diabetes medicine.
The hormone insulin is released from the pancreas. It helps the body convert sugars into energy for use. Different types of diabetes are caused by different types of insulin-related disorders.
1. Diabetes type 1, usually seen in children. It occurs when the body cannot make insulin.
2. Diabetes type 2, commonly seen in overweight adults, occurs when the body cannot use insulin properly.
3. Gestational diabetes is seen in pregnant women, due to placental hormones, the level of insulin goes to such a level that the body can not use it effectively.

Hepatic steatosis (fatty liver), bladder disease (excess blood sugar puts pressure on the kidneys), and even heart disease (damage to arteries due to excess blood sugar) can cause all sorts of diabetes complications.
The discovery of insulin and its role in diabetes was a groundbreaking treatment that won several Nobel Prize winners. In their study, Oscar Minkowski and Joseph von Mering found that dogs whose pancreas was removed had diabetes. The study was explained by Frederick Banting and Charles Best, who saved diabetic dogs with pancreatic extract in saline solution, and finally, James Collip and John McLeod collected insulin from calf pancreas, purified it for purification, and used it for human consumption…

In January 1922, Leonard Thompson, a 14-year-old man with a diabetic condition, was diagnosed with a severe form of diabetes. Within 24 hours of receiving the first dose of refined insulin, her blood sugar level skyrocketed to 520 mg/dl and then dropped to just 120 mg/dl. Surviving Leonard Thompson’s death for insulin has become a beacon of hope for all diabetics around the world.

Since 1982, it has no longer been dependent on animals for insulin production. Advances in genetic engineering have made it possible for bacteria to produce human insulin. The insulin pen was invented in 1975, with significant improvements in efficiency, benefits, and the ultimate guarantee of life for diabetics. It has further improved the quality of life of diabetics and their families by making it possible for them to take insulin according to their own daily schedule and activities. In fact, insulin has come a long way in 100 years.

In addition to insulin, there is a bright medical success for diabetics, which is more effective than insulin and the drug can be taken orally. This newly invented diabetes medicine has the following effects in different types: –
Reduces the amount of sugar released by the liver into the blood
Prolongs the effectiveness of insulin in the body
Stimulates the production of insulin
Prolongs the effectiveness of insulin in the body
Decreasing the reabsorption of glucose in the kidneys
These oral anti-diabetic drugs are much more convenient to store, transport, and administer than insulin. Adoption has become rapid and widespread, especially among patients with mild diabetes.

However, the risk of diabetes is not limited to high blood sugar levels. There is also a risk of diabetes from bladder disease, liver disease, and heart disease. This is why diabetes medicine today doesn’t just focus on blood sugar levels. Instead, they are addressing a whole host of other systemic health issues for diabetic patients, with the regulatory authority mandating this new approach to drug approval. The latest invention of the drug has proven its effectiveness not only in its very low side effects but also in its undeniable role in the small number of hospital admissions and low mortality from diabetic heart disease.

What has emerged in the 100-year history of insulin is the determination and skill of some of the best people in science and medicine to fight diabetes. Boomerangrad International Hospital is proud to be a part of its ongoing efforts to improve the quality of life of diabetics. We continue to work tirelessly to bring the latest advances in the treatment of our patients, so much so that we continue to carry the old flame with insulin to that young boy with diabetes in the first century.

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