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Will be released without drugs forever!

 Will be released without drugs forever!

Diabetes is a physical condition that lasts a lifetime. The disease kills more than one million people worldwide every year. Diabetes occurs when the body fails to break down all the blood sugar (glucose). This complication can lead to heart attack and stroke. In addition, diabetes can lead to blindness and damage to the kidneys. According to a new study, it is possible to get rid of type 2 diabetes forever without medication. Although more research is needed


Between 1980 and 2014, the number of diabetics worldwide increased from 11 crores to 42.2 crores. Of these, 90 percent are people with type 2 diabetes. Although diabetes is referred to as an epidemic, the activity to overcome the disease is very limited. Experts say that even if any other method of controlling diabetes fails, eating habits and lifestyle changes can be successful.


The first results of a clinical trial published a few years ago showed that it is possible to get rid of type 2 diabetes through intensive weight loss without taking any medication. The trial is called the Diabetes Remission Clinical Trial and was co-sponsored by Professor Roy Taylor of the University of Newcastle in the United Kingdom. But how does this relief happen and can it be lasting? Why do some people get permanent relief from others? Or can the disease come back again? Using clinical trial data, cutting-edge imaging and blood monitoring techniques, Professor Taylor and his team began searching for answers to these questions. The study was recently published in the journal Cell Metabolism.

‘Twin Cycle Hypothesis’ test

The aim of the study was to re-examine the ‘twin cycle hypothesis of Professor Taylor and his team, published more than a decade ago. The study suggested that the accumulation of fat in the liver results in type 2 diabetes, which inhibits insulin and increases blood sugar production.


Due to this increased level of liver fats, lipids spread to several tissues, including the pancreas. And the location of the beta cells that make insulin is in the pancreas. This is why the long-term release of saturated fatty acids is harmful to beta cells. The researchers wanted to describe the main pathophysiological processes of recurrence of type 2 diabetes, which, although initially cured, came back. To find out, the researchers measured intracellular and abdominal fat using MRI scans for 12-14 months. In particular, they observed pancreatic and liver fat.


The analysis included measurements of glucose, HbA1c, high-density lipoprotein (HDL) cholesterol, and triglycerides. The team also analyzed fatty acids, insulin secretion, and beta-cell function.

Liver fat paralyzes the pancreas

The study found that the vast majority of people who took the test did not have diabetes for more than two years, but only because they had lower liver and intestinal fat. In particular, nine out of 10 people who were able to lose 15 kg or more in clinical trials got this result. Two years later, more than one-third of the participants were diabetic. However, it takes 24 consecutive months to take diabetes medication. However, those who returned with diabetes had higher liver triglycerides and higher intrapancreatic fat levels.


Professor Taylor explained, “Studies have shown that when fat accumulates in a person’s body, it tends to be stored safely under the skin. It can then go to any part of the body as needed. The amount of fat stored under the skin varies from person to person, this is called the ‘personal fat threshold’. However, when it exceeds a certain amount, fat becomes the cause of loss. ‘


“When there is a certain amount of fat under the skin, it is stored inside the liver and spreads to other parts of the body, including the pancreas,” he said. It completely blocks or paralyzes the pancreas and shuts down the genes involved in making effective insulin. This is the cause of type 2 diabetes. ‘

 ‘Diet and sticking to it is a permanent solution

Researcher Roy Taylor emphasizes that the results of the study mean that we now see simple formulas for type 2 diabetes, where a person accumulates more fat than a certain amount. In this case, by diet and keeping it, patients are able to reduce fat and say goodbye to their diabetes forever. The faster the fat is reduced, the lower the risk of loss.


Professor Taylor and his team concluded the study by saying, “For the first time, we have been able to uncover the underlying physiological changes that occur during the entire cycle of disease outbreaks and relapses.”


To test this out, the US National Health Service (NHS) will create a program to test thousands of people with type 2 diabetes for weight loss therapy.

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